Lymphomatoid granulomatosis involving lung and brain in an immunocompetent woman

Axial T2 and enhanced T1 MRI demonstrating cerebellar T2 hyperintensity and stippled enhancement; FDG-PET avid lung lesion (arrow)
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Rhomboencephalitis due to cocaine-induced bony erosion of skull base

Sagittal T2 (A), axial T2 fluid-attenuated inversion recovery (B), and sagittal T1 with contrast MRI (C) show a large bony defect in the skull base with erosion of the sphenoid sinus walls and perforated nasal septum. There is abnormal T2 hyperintensity and enhancement in the brainstem with clival erosion (arrow where most severe) and marrow enhancement.
Axial T2 fluid-attenuated inversion recovery MRI of the brain demonstrates decreased T2 fluid-attenuated inversion recovery hyperintensity in the medulla following 6 weeks of IV antibiotics.

Anterior horn cell hyperintensity in Hirayama disease

(A) Abnormal kyphotic (straight) curvature of the cervical spine evidenced by dorsal aspects of the C3 through C6 vertebral bodies meeting a straight line (white) drawn from the dorsocaudal aspect of the C2 vertebral body to the dorsocaudal aspect of the vertebral body of C7. In addition, note the linear T2 intramedullary hyperintensity, representing atrophy and gliosis of the anterior horn cells (large arrow). (B) Transverse T2-weighted image demonstrating the owl eyes sign (hyperintensities in the anterior horns of gray matter), representing atrophy and gliosis of the anterior horn cells (white arrows)